Pub. Date : 2020
PMID : 33381031
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Suppression of Urokinase-Type Plasminogen Activator Receptor by Docosahexaenoic Acid Mediated by Heme Oxygenase-1 in 12-O-Tetradecanoylphorbol-13-Acetate-Induced Human Endothelial Cells. | Docosahexaenoic Acids | heme oxygenase 1 | Homo sapiens |
| 2 | The aim of this study was to investigate the effect of DHA on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced uPAR expression and potential role of heme oxygenase-1 (HO-1) in DHA-induced inhibition of uPAR in human endothelial ECV304 cells. | Docosahexaenoic Acids | heme oxygenase 1 | Homo sapiens |
| 3 | The aim of this study was to investigate the effect of DHA on 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced uPAR expression and potential role of heme oxygenase-1 (HO-1) in DHA-induced inhibition of uPAR in human endothelial ECV304 cells. | Docosahexaenoic Acids | heme oxygenase 1 | Homo sapiens |
| 4 | Moreover, treatment with DHA induced HO-1 expression in a time- and concentration-dependent manner. | Docosahexaenoic Acids | heme oxygenase 1 | Homo sapiens |
| 5 | In addition, DHA-induced inhibition of uPAR expression and cell invasion in TPA-stimulated cells was reversed by si-HO-1 RNA. | Docosahexaenoic Acids | heme oxygenase 1 | Homo sapiens |
| 6 | Collectively, these data suggest a novel role of DHA-induced HO-1 in reducing uPAR expression and cell invasion in human endothelial ECV304 cells. | Docosahexaenoic Acids | heme oxygenase 1 | Homo sapiens |