Pub. Date : 2020
PMID : 33376736
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | From pairwise and network meta-analyses, buparlisib showed the most favorable ORR, as it was significantly different from fulvestrant in the PIK3CA-mutated patient group (2.80, 1.56 to 5.03). | NVP-BKM120 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Homo sapiens |
| 2 | Conclusion: The PI3K inhibitors alpelisib and buparlisib appear to have superior efficacy and safety therapeutic choices for patients with BC, especially in PIK3CA-mutated patients. | NVP-BKM120 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Homo sapiens |