Pub. Date : 2020 Dec 23
PMID : 33374508
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The AHR has historically been studied within the context of potent activation via AHR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), with a focus on how the AHR mediates TCDD toxicity. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 2 | The AHR has historically been studied within the context of potent activation via AHR agonist 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), with a focus on how the AHR mediates TCDD toxicity. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 3 | In this review, we re-trace the steps through which the early toxicological studies of TCDD led to the conceptual framework for the AHR as a potential therapeutic target in metabolic disease. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |