Pub. Date : 2021 Feb
PMID : 33360300
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | MicroRNA-506-3p increases the response to PARP inhibitors and cisplatin by targeting EZH2/beta-catenin in serous ovarian cancers. | Cisplatin | catenin beta 1 | Homo sapiens |
| 2 | MiR-506-3p overexpression decreased the level of beta-catenin, and the sensitivity to olaparib and cisplatin mediated by miR-506-3p was partially reversed by regulating beta-catenin expression in ovarian cancer. | Cisplatin | catenin beta 1 | Homo sapiens |
| 3 | MiR-506-3p overexpression decreased the level of beta-catenin, and the sensitivity to olaparib and cisplatin mediated by miR-506-3p was partially reversed by regulating beta-catenin expression in ovarian cancer. | Cisplatin | catenin beta 1 | Homo sapiens |
| 4 | Our results suggest that miR-506-3p increases response to PARP inhibitors and cisplatin in serous ovarian cancer by targeting EZH2/beta-catenin signal pathway, which opens the possibility of using miR-506-3p overexpression as a potential therapeutic for ovarian cancer. | Cisplatin | catenin beta 1 | Homo sapiens |