Pub. Date : 2021 Mar 1
PMID : 33358903
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | miR-485-3p regulated by MALAT1 inhibits osteosarcoma glycolysis and metastasis by directly suppressing c-MET and AKT3/mTOR signalling. | mir-485-3p | AKT serine/threonine kinase 3 | Homo sapiens |
| 2 | miR-485-3p bound directly to c-MET and AKT3 mRNAs and repressed OS cell glycolysis, proliferation, migration, and invasion through decreasing glycolysis-related proteins and migration-related proteins via inhibiting c-MET and AKT3/mTOR pathway. | mir-485-3p | AKT serine/threonine kinase 3 | Homo sapiens |
| 3 | miR-485-3p bound directly to c-MET and AKT3 mRNAs and repressed OS cell glycolysis, proliferation, migration, and invasion through decreasing glycolysis-related proteins and migration-related proteins via inhibiting c-MET and AKT3/mTOR pathway. | mir-485-3p | AKT serine/threonine kinase 3 | Homo sapiens |
| 4 | SIGNIFICANCE: miR-485-3p suppresses OS glycolysis, proliferation, and metastasis via inhibiting c-MET and AKT3/mTOR signalling and MALAT1 acts as a sponge of miR-485-3p. | mir-485-3p | AKT serine/threonine kinase 3 | Homo sapiens |