Protein Name AKT serine/threonine kinase 3
Organism Homo sapiens
Gene ID 10000
Gene Symbol

AKT3

UniProt Q9Y243 (AKT3_HUMAN), A0A5F9ZHU3 (A0A5F9ZHU3_HUMAN)
Relationships Total Number of functionally related compound(s) : 98
Total Number of Articles : 100
Description

AKT serine/threonine kinase 3

Gene Summary

The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

synonyms
  • RAC-gamma serine/threonine-protein kinase
  • PKB gamma
  • RAC-gamma serine/threonine protein kinase
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Properties