Title : Nicaraven inhibits TNFα-induced endothelial activation and inflammation through suppression of NF-κB signaling pathway.

Pub. Date : 2021 Aug

PMID : 33356884






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Nicaraven suppressed TNFalpha-induced mRNA expression of multiple adhesion molecules and pro-inflammatory cytokines, including VCAM-1, ICAM-1, E-selectin, MCP-1, TNFalpha, IL-1beta, IL-6 and IL-8. nicaraven vascular cell adhesion molecule 1 Homo sapiens
2 In addition, Nicaraven inhibited monocyte adhesion and reduced the protein levels of VCAM-1 and ICAM-1. nicaraven vascular cell adhesion molecule 1 Homo sapiens