Protein Name vascular cell adhesion molecule 1
Organism Homo sapiens
Gene ID 7412
Gene Symbol

VCAM1

UniProt P19320 (VCAM1_HUMAN)
Relationships Total Number of functionally related compound(s) : 1154
Total Number of Articles : 1563
Description

vascular cell adhesion molecule 1

Gene Summary

This gene is a member of the Ig superfamily and encodes a cell surface sialoglycoprotein expressed by cytokine-activated endothelium. This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction, and may play a role in the development of artherosclerosis and rheumatoid arthritis. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Dec 2010]

synonyms
  • vascular cell adhesion protein 1
  • CD106 antigen
  • CD106
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Properties