Title : Redox regulation of immunometabolism.

Pub. Date : 2021 Jun

PMID : 33340021






2 Functional Relationships(s)
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1 Here, we summarize recent insights revealing the role of reactive oxygen species (ROS) and the differential requirement of the main cellular antioxidant pathways, including the components of the thioredoxin (TRX) and glutathione (GSH) pathways, as well as their transcriptional regulator NF-E2-related factor 2 (NRF2), for proliferation, survival and function of T cells, B cells and macrophages. Glutathione NFE2 like bZIP transcription factor 2 Homo sapiens
2 Here, we summarize recent insights revealing the role of reactive oxygen species (ROS) and the differential requirement of the main cellular antioxidant pathways, including the components of the thioredoxin (TRX) and glutathione (GSH) pathways, as well as their transcriptional regulator NF-E2-related factor 2 (NRF2), for proliferation, survival and function of T cells, B cells and macrophages. Glutathione NFE2 like bZIP transcription factor 2 Homo sapiens