Title : α-Conotoxin TxID and [S9K]TxID, α3β4 nAChR Antagonists, Attenuate Expression and Reinstatement of Nicotine-Induced Conditioned Place Preference in Mice.

Pub. Date : 2020 Dec 16

PMID : 33339145






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The alpha3beta4 nicotinic acetylcholine receptor (nAChR) is strongly associated with nicotine reward and withdrawal symptom. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
2 The present experiment investigates the effect of alpha3beta4 nAChR antagonists (TxID and [S9K]TxID) on the expression and reinstatement of nicotine-induced conditioned place preference (CPP) and explores the behaviors of acute nicotine in mice. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus
3 Therefore, these findings reveal that the alpha3beta4 nAChR may be a potential target for anti-nicotine addiction treatment. Nicotine cholinergic receptor, nicotinic, alpha polypeptide 7 Mus musculus