Pub. Date : 2021 Jan
PMID : 33338921
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In proliferating Caco-2 cells, Hex acted attenuating EGF-induced EGFR dimerization and NADPH oxidase-dependent phosphorylation at Tyr 1068, decreasing EGFR location at lipid rafts, and inhibiting the downstream activation of pro-proliferative and anti-apoptotic pathways, i.e. Raf/MEK/ERK1/2 and PI3K/Akt. | Tyrosine | epidermal growth factor | Homo sapiens |