Title : Salvianolate ameliorates oxidative stress and podocyte injury through modulation of NOX4 activity in db/db mice.

Pub. Date : 2021 Jan

PMID : 33332718






1 Functional Relationships(s)
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1 In human podocytes, NOX4 was predominantly localized to mitochondria and Sal B treatment blocked HG-induced mitochondrial NOX4 derived superoxide generation and thereby ameliorating podocyte apoptosis, which can be abrogated by AMPK knockdown. Superoxides NADPH oxidase 4 Homo sapiens