Title : Betulinic Acid Ameliorates the T-2 Toxin-Triggered Intestinal Impairment in Mice by Inhibiting Inflammation and Mucosal Barrier Dysfunction through the NF-κB Signaling Pathway.

Pub. Date : 2020 Dec 13

PMID : 33322178






1 Functional Relationships(s)
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1 Furthermore, treatment with 1 mg/kg BA downregulated the expression of p-NF-kappaB and p-IkappaB-alpha proteins in the intestine, while all doses of BA suppressed the pro-inflammatory cytokines expression of IL-1beta, IL-6 and TNF-alpha mRNAs and increased the anti-inflammatory cytokine expression of IL-10 mRNA in the intestine of T-2 toxin-exposed mice. betulinic acid interleukin 1 alpha Mus musculus