Title : Modulation of CYP3A4 and CYP2C9 activity by Bulbine natalensis and its constituents: An assessment of HDI risk of B. natalensis containing supplements.

Pub. Date : 2021 Jan

PMID : 33321412






1 Functional Relationships(s)
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1 In a CYP inhibition assay, the methanolic extract as well as the anthraquinones strongly inhibited the catalytic activity of CYP2C9 while, inhibition of CYP3A4 was weak. Anthraquinones cytochrome P450 family 3 subfamily A member 4 Homo sapiens