Title : Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5.

Pub. Date : 2020 Dec 8

PMID : 33296647






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Cyclic guanosine monophosphate (GMP)-AMP synthase (cGAS), upon sensing cytosolic DNA, catalyzes the production of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP), which activates STING-TBK1-IRF3 signaling. Guanosine Monophosphate interferon regulatory factor 3 Homo sapiens