Title : Participation of Endosomes in Toll-Like Receptor 3 Transportation Pathway in Murine Astrocytes.

Pub. Date : 2020

PMID : 33281554






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TLR3 was transported rapidly to early EEA1-positive endosomes as well as LAMP1-lysosomes following stimulation with the poly(I:C). Poly I-C toll-like receptor 3 Mus musculus
2 TLR3 interacted with poly(I:C) intracellularly from 1 min to 8 h following cell stimulation. Poly I-C toll-like receptor 3 Mus musculus
3 We detected TLR3 on the surface of astrocytes indicating constitutive expression, which increased after poly(I:C) stimulation. Poly I-C toll-like receptor 3 Mus musculus