Title : IP3R Channels in Male Reproduction.

Pub. Date : 2020 Dec 2

PMID : 33276427






7 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Inositol 1,4,5-trisphosphate receptor (IP3R) is a widely expressed channel for calcium stores. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens
2 After being activated by inositol 1,4,5-trisphosphate (IP3) and calcium signaling at a lower concentration, IP3R can regulate the release of Ca2+ from stores into cytoplasm, and eventually trigger downstream events. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens
3 The closure of the IP3R channel caused by a rise in intracellular calcium signals and the activation of the calcium pump jointly restores the calcium store to a normal level. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens
4 The closure of the IP3R channel caused by a rise in intracellular calcium signals and the activation of the calcium pump jointly restores the calcium store to a normal level. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens
5 The closure of the IP3R channel caused by a rise in intracellular calcium signals and the activation of the calcium pump jointly restores the calcium store to a normal level. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens
6 In this review, we aim to discuss structural features of IP3R channels and the underlying mechanism of IP3R channel-mediated calcium signaling and further focus on the research progress of IP3R expression and function in the male reproductive system. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens
7 In this review, we aim to discuss structural features of IP3R channels and the underlying mechanism of IP3R channel-mediated calcium signaling and further focus on the research progress of IP3R expression and function in the male reproductive system. Calcium inositol 1,4,5-trisphosphate receptor type 3 Homo sapiens