Title : NLRP3 inflammasome deficiency attenuates metabolic disturbances involving alterations in the gut microbial profile in mice exposed to high fat diet.

Pub. Date : 2020 Dec 3

PMID : 33273482






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Obese NLRP3 deficient mice had lower systemic ceramide levels, potentially resulting attenuating inflammation, altered hepatic expression of fatty acids (FA) with lower mono-saturated FA and higher polyunsaturated FA levels, potentially counteracting development of liver steatosis, downregulated myocardial energy metabolism as assessed by proteomic analyses of LV heart tissue, and different levels of bile acids as compared with WT mice. Fatty Acids NLR family, pyrin domain containing 3 Mus musculus