Title : Activation of PI3K/Akt/HIF-1α Signaling is Involved in Lung Protection of Dexmedetomidine in Patients Undergoing Video-Assisted Thoracoscopic Surgery: A Pilot Study.

Pub. Date : 2020

PMID : 33262576






1 Functional Relationships(s)
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1 DEX alleviated the alveolar capillary epithelial structure damage, increased protein expression of ZO-1 and occludin, inhibited elevation of the expression of TNF-alpha and IL-6 in lung tissue and plasma, and increased protein expression of p-PI3K, p-AKT and HIF-1alpha. Dexmedetomidine interleukin 6 Homo sapiens