Pub. Date : 2020 Nov 25
PMID : 33255747
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Distinct membrane receptors activate platelets by Src-family-kinase (SFK)-, immunoreceptor-tyrosine-based-activation-motif (ITAM)-dependent stimulation of spleen tyrosine kinase (Syk). | Tyrosine | spleen associated tyrosine kinase | Homo sapiens |
2 | Distinct membrane receptors activate platelets by Src-family-kinase (SFK)-, immunoreceptor-tyrosine-based-activation-motif (ITAM)-dependent stimulation of spleen tyrosine kinase (Syk). | Tyrosine | spleen associated tyrosine kinase | Homo sapiens |
3 | Recently, we reported that platelet activation via glycoprotein (GP) VI or GPIbalpha stimulated the well-established Syk tyrosine (Y)-phosphorylation, but also stoichiometric, transient protein kinase C (PKC)-mediated Syk serine(S)297 phosphorylation in the regulatory interdomain-B, suggesting possible feedback inhibition. | Tyrosine | spleen associated tyrosine kinase | Homo sapiens |