Title : COX-2 Is Downregulated in Human Stenotic Aortic Valves and Its Inhibition Promotes Dystrophic Calcification.

Pub. Date : 2020 Nov 24

PMID : 33255450






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Furthermore, we observed that COX-2 inhibition with celecoxib induces AVICs trans-differentiation towards a myofibroblast phenotype, and increases the levels of TGF-beta-induced apoptosis, both processes able to promote the formation of calcific nodules. Celecoxib transforming growth factor alpha Homo sapiens