Title : MEK inhibitors reduce cellular expression of ACE2, pERK, pRb while stimulating NK-mediated cytotoxicity and attenuating inflammatory cytokines relevant to SARS-CoV-2 infection.

Pub. Date : 2020 Nov 17

PMID : 33245731






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 TMPRSS2, inflammatory cytokines G-CSF, M-CSF, IL-1alpha, IL-6 and MCP-1 are suppressed by MEKi alone or with remdesivir. remdesivir interleukin 1 alpha Homo sapiens