Title : Zinc complexation improves angiotensin II receptor type 1 blockade and in vivo antihypertensive activity of telmisartan.

Pub. Date : 2021 Jan

PMID : 33243020






1 Functional Relationships(s)
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1 Results: Compared with telmisartan, ZnTelm displayed stronger binding to AT1R (binding studies on AT1R-transfected human embryonic kidney cells) and a greater reduction of reactive oxygen species and cytosolic calcium concentration induced by angiotensin II. Reactive Oxygen Species angiotensinogen Homo sapiens