Pub. Date : 2020 Nov 24
PMID : 33238129
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, we find that BRAF(V600E) mutant melanoma persister cells tolerant to BRAF/MEK inhibitors switch their metabolism from glycolysis to oxidative respiration supported by peroxisomal fatty acid beta-oxidation (FAO) that is transcriptionally regulated by peroxisome proliferator-activated receptor alpha (PPARalpha). | Fatty Acids | peroxisome proliferator activated receptor alpha | Homo sapiens |
| 2 | Here, we find that BRAF(V600E) mutant melanoma persister cells tolerant to BRAF/MEK inhibitors switch their metabolism from glycolysis to oxidative respiration supported by peroxisomal fatty acid beta-oxidation (FAO) that is transcriptionally regulated by peroxisome proliferator-activated receptor alpha (PPARalpha). | Fatty Acids | peroxisome proliferator activated receptor alpha | Homo sapiens |