Pub. Date : 2021 Apr 13
PMID : 33230523
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Evolution of Hominin Detoxification: Neanderthal and Modern Human Ah Receptor Respond Similarly to TCDD. | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 2 | To evaluate this, we compared the AHR-controlled induction of cytochrome P4501A1 (CYP1A1) mRNA in HeLa human cervix epithelial adenocarcinoma cells transfected with an Altai-Neanderthal or a modern human reference AHR expression construct, and exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |
| 3 | To evaluate this, we compared the AHR-controlled induction of cytochrome P4501A1 (CYP1A1) mRNA in HeLa human cervix epithelial adenocarcinoma cells transfected with an Altai-Neanderthal or a modern human reference AHR expression construct, and exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). | Polychlorinated Dibenzodioxins | aryl hydrocarbon receptor | Homo sapiens |