Pub. Date : 2020
PMID : 33224612
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Evaluation of the use of sitagliptin for insulin resistance in burn patients. | Sitagliptin Phosphate | insulin | Homo sapiens |
| 2 | Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that improves glycemic control by slowing the inactivation of incretin hormones, increasing insulin synthesis and release from pancreatic beta cells and lowering glucagon secretion from pancreatic alpha cells. | Sitagliptin Phosphate | insulin | Homo sapiens |
| 3 | The objective of this study was to describe our institution"s experience with using sitagliptin to help mitigate insulin resistance after burn injury. | Sitagliptin Phosphate | insulin | Homo sapiens |
| 4 | In the 3 days after sitagliptin was started, exogenous insulin requirements significantly decreased to a median to 36.3 units per day (IQR 11.7, 95) (P=0.009). | Sitagliptin Phosphate | insulin | Homo sapiens |
| 5 | After sitagliptin was started, it took a median of 3 days (IQR 2, 3.25) to be liberated from the insulin infusion. | Sitagliptin Phosphate | insulin | Homo sapiens |
| 6 | CONCLUSION: The addition of sitagliptin to burn patients" medication regimens significantly reduced insulin requirements over a 3-day period and allowed liberation from insulin drips. | Sitagliptin Phosphate | insulin | Homo sapiens |
| 7 | CONCLUSION: The addition of sitagliptin to burn patients" medication regimens significantly reduced insulin requirements over a 3-day period and allowed liberation from insulin drips. | Sitagliptin Phosphate | insulin | Homo sapiens |