Pub. Date : 2021 Jan
PMID : 33223341
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | A Guillain-Barre syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides. | Gangliosides | sialic acid binding Ig like lectin 10 | Homo sapiens |
2 | Recombinant Siglec-10 protein containing R47Q but not A108V shows impaired binding to gangliosides. | Gangliosides | sialic acid binding Ig like lectin 10 | Homo sapiens |
3 | Because Siglec-10 regulates antibody production to sialylated antigens, our finding suggests that Siglec-10 regulates development of GBS by suppressing antibody production to gangliosides, with defects in its function predisposing to disease. | Gangliosides | sialic acid binding Ig like lectin 10 | Homo sapiens |
4 | Because Siglec-10 regulates antibody production to sialylated antigens, our finding suggests that Siglec-10 regulates development of GBS by suppressing antibody production to gangliosides, with defects in its function predisposing to disease. | Gangliosides | sialic acid binding Ig like lectin 10 | Homo sapiens |