PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 33223341-0 2021 A Guillain-Barre syndrome-associated SIGLEC10 rare variant impairs its recognition of gangliosides. Gangliosides 86-98 sialic acid binding Ig like lectin 10 Homo sapiens 37-45 33223341-7 2021 Recombinant Siglec-10 protein containing R47Q but not A108V shows impaired binding to gangliosides. Gangliosides 86-98 sialic acid binding Ig like lectin 10 Homo sapiens 12-21 33223341-10 2021 Because Siglec-10 regulates antibody production to sialylated antigens, our finding suggests that Siglec-10 regulates development of GBS by suppressing antibody production to gangliosides, with defects in its function predisposing to disease. Gangliosides 175-187 sialic acid binding Ig like lectin 10 Homo sapiens 8-17 33223341-10 2021 Because Siglec-10 regulates antibody production to sialylated antigens, our finding suggests that Siglec-10 regulates development of GBS by suppressing antibody production to gangliosides, with defects in its function predisposing to disease. Gangliosides 175-187 sialic acid binding Ig like lectin 10 Homo sapiens 98-107