Title : PPARα Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates.

Pub. Date : 2020 Nov 20

PMID : 33205029






3 Functional Relationships(s)
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1 PPARalpha Ligand-Binding Domain Structures with Endogenous Fatty Acids and Fibrates. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
2 Here we show thirty-four X-ray crystallographic structures of the PPARalpha ligand-binding domain, which are composed of a "Center" and four "Arm" regions, in complexes with five endogenous fatty acids, six fibrates in clinical use, and six synthetic PPARalpha agonists. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens
3 Here we show thirty-four X-ray crystallographic structures of the PPARalpha ligand-binding domain, which are composed of a "Center" and four "Arm" regions, in complexes with five endogenous fatty acids, six fibrates in clinical use, and six synthetic PPARalpha agonists. Fatty Acids peroxisome proliferator activated receptor alpha Homo sapiens