Title : Potent Clastogenicity of Bisphenol Compounds in Mammalian Cells-Human CYP1A1 Being a Major Activating Enzyme.

Pub. Date : 2020 Dec 1

PMID : 33201683






1 Functional Relationships(s)
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1 In V79-hCYP1A1 and C3A cells, all compounds induced double-strand DNA breaks and micronuclei formation, which were blocked/significantly attenuated by 1-aminobenzotriazole (CYP inhibitor) or 7-hydroxyflavone (selective CYP1A1 inhibitor). 7-hydroxyflavone cytochrome P450 family 1 subfamily A member 1 Homo sapiens