Title : [Therapeutic possibilities in KRAS-mutant lung adenocarcinoma].

Pub. Date : 2020 Sep 23

PMID : 33196710






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Although the different mutations of the KRAS gene have been identified decades ago, the development of drugs targeting the KRAS protein directly have not been successful due to the lack of small molecule binding sites and the extremely high affinity to cellular GTP. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens
2 Although the different mutations of the KRAS gene have been identified decades ago, the development of drugs targeting the KRAS protein directly have not been successful due to the lack of small molecule binding sites and the extremely high affinity to cellular GTP. Guanosine Triphosphate KRAS proto-oncogene, GTPase Homo sapiens