Title : CBP-mediated Wnt3a/β-catenin signaling promotes cervical oncogenesis initiated by Piwil2.

Pub. Date : 2021 Jan

PMID : 33190089






1 Functional Relationships(s)
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1 Blocking the beta-catenin and CREB binding protein interaction with ICG-001 significantly downregulated the reprogramming factors c-Myc, Nanog, Oct4, Sox2, and Klf4, thus leading to cell differentiation and preventing tumorigenicity in Piwil2-overexpressing HaCaT cells. ICG 001 POU class 5 homeobox 1 Homo sapiens