Title : Combined targeting of the p53 and pRb pathway in neuroblastoma does not lead to synergistic responses.

Pub. Date : 2021 Jan

PMID : 33190064






1 Functional Relationships(s)
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1 In our panel of ten cell lines with a spectrum of aberrations in the p53 and pRb pathway, idasanutlin and abemaciclib were the most potent MDM2 and CDK4/6 inhibitors, respectively. RG7388 cyclin dependent kinase 4 Homo sapiens