Pub. Date : 2018 Jan 30
PMID : 33177018
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | [Effect of MDR1 and CYP3A5 gene polymorphisms on outcomes of patients receiving imatinib treatment for chronic myeloid leukemia]. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
2 | OBJECTIVE: To study the effect of MDR1 and CYP3A5 gene polymorphisms on the outcomes of imatinib treatment in patients with chronic myeloid leukemia (CML). | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |
3 | CONCLUSIONS: The risk of cytogenetic relapse of CML was significantly affected by SNPs of C1236T and C3435T loci of MDR1 gene and blood imatinib concentration. | Imatinib Mesylate | ATP binding cassette subfamily B member 1 | Homo sapiens |