Pub. Date : 2020 Nov 7
PMID : 33176281
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Puerarin alleviates osteoporosis in the ovariectomy-induced mice by suppressing osteoclastogenesis via inhibition of TRAF6/ROS-dependent MAPK/NF-kappaB signaling pathways. | puerarin | TNF receptor-associated factor 6 | Mus musculus |
| 2 | Puerarin inhibited TRAF6/ROS-dependent activation of the MAPK and NF-kappaB signaling pathways in RANKL-induced RAW264.7 cells, and these effects were partially reversed by HO-1 silencing or TRAF6 overexpression. | puerarin | TNF receptor-associated factor 6 | Mus musculus |
| 3 | Puerarin inhibited TRAF6/ROS-dependent activation of the MAPK and NF-kappaB signaling pathways in RANKL-induced RAW264.7 cells, and these effects were partially reversed by HO-1 silencing or TRAF6 overexpression. | puerarin | TNF receptor-associated factor 6 | Mus musculus |
| 4 | These findings suggest puerarin alleviates loss of bone mass in the OVX-model mice by suppressing osteoclastogenesis via inhibition of the TRAF6/ROS-dependent MAPK/NF-kappaB signaling pathway. | puerarin | TNF receptor-associated factor 6 | Mus musculus |