Title : Metformin as a potential therapeutic for neurological disease: mobilizing AMPK to repair the nervous system.

Pub. Date : 2021 Jan

PMID : 33161784






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1 Areas covered: The authors review literature on metformin treatment in Parkinson"s disease, Huntington"s disease and other neurological diseases of the CNS along with neuroprotective effects of AMPK activation and suppression of the mammalian target of rapamycin (mTOR) pathway on peripheral neuropathy and neuropathic pain. Metformin mechanistic target of rapamycin kinase Homo sapiens