Pub. Date : 2021 Mar
PMID : 33160044
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | RESULTS: The results suggested that HCQ in the treatment of RA was mainly associated with 4 targets that are smoothened homolog (SMO), sphingosine kinase (SPHK) 1, SPHK2 and gatty-acid amide hydrolase (FAAH), with their related 3276 proteins" network which regulate ErbB, HIF-1, NF-kappaB, FoxO, chemokines, MAPK, PI3K/Akt pathways and so forth. | Hydroxychloroquine | sphingosine kinase 2 | Homo sapiens |
| 2 | SMO, SPHK1, SPHK2 and FAAH involving 3276 proteins become the multi-targets mechanism of HCQ in the treatment of RA. | Hydroxychloroquine | sphingosine kinase 2 | Homo sapiens |