Title : Modified bile acids and androstanes-Novel promising inhibitors of human cytochrome P450 17A1.

Pub. Date : 2021 Jan

PMID : 33157220






1 Functional Relationships(s)
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1 Results presented here showed that these steroidal compounds are able to decrease rate of hydroxylation of essential CYP17A1 substrate - progesterone, while some compounds completely inhibited enzyme activity. Progesterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens