Title : Kirenol, darutoside and hesperidin contribute to the anti-inflammatory and analgesic activities of Siegesbeckia pubescens makino by inhibiting COX-2 expression and inflammatory cell infiltration.

Pub. Date : 2021 Mar 25

PMID : 33152433






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 (2) Both the ESM and its active ingredients could effectively alleviate the degree of swelling of the auricle and toes, increase the threshold of heat pain, decrease the overexpression of inflammatory protein cyclooxygenase-2 (COX-2) in the skin tissue of the tested parts of the toes, and reduce the number of writhes induced by acetic acid in mice. Acetic Acid prostaglandin-endoperoxide synthase 2 Mus musculus