Pub. Date : 2020 Oct 31
PMID : 33142935
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Label-Free Oligonucleotide-Based SPR Biosensor for the Detection of the Gene Mutation Causing Prothrombin-Related Thrombophilia. | Oligonucleotides | coagulation factor II, thrombin | Homo sapiens |
| 2 | In this work, a glass chip covered with an ultrathin (50 nm) gold film was modified with oligonucleotide strands complementary to the mutated or normal (nonmutated) DNA responsible for prothrombin-related thrombophilia, forming two detection platforms called mutated thrombophilia (MT) biosensor and normal thrombophilia (NT) biosensor. | Oligonucleotides | coagulation factor II, thrombin | Homo sapiens |
| 3 | This work contributes to the design of the first SPR biosensor for the detection of prothrombin-related thrombophilia based on oligonucleotides with single point mutations, label-free and without the need to apply an amplification method. | Oligonucleotides | coagulation factor II, thrombin | Homo sapiens |