Pub. Date : 2021 Jan
PMID : 33137541
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Targeted inhibition of glutamine metabolism enhances the antitumor effect of selumetinib in KRAS-mutant NSCLC. | AZD 6244 | KRAS proto-oncogene, GTPase | Homo sapiens |
| 2 | CB839, an efficient glutaminase inhibitor, synergized with the MEK inhibitor selumetinib to enhance antitumor activity in KRAS-mutant NSCLC cells and xenografts, and the therapeutic response could be well identified by 18F-FDG PET imaging. | AZD 6244 | KRAS proto-oncogene, GTPase | Homo sapiens |