Pub. Date : 2020 Oct 30
PMID : 33126860
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The aim of this study was to determine whether GTS-21 (3-(2,4-dimethoxybenzylidene) anabaseine), an alpha7 nicotinic acetylcholine receptor (alpha7nAChR) agonist, could (1) inhibit hyperoxia-induced HMGB1 release into the airways; (2) enhance macrophage phagocytosis and (3) increase bacterial clearance from the lungs in a mouse model of ventilator-associated pneumonia. | 3-(2,4-dimethoxybenzylidene)anabaseine | cholinergic receptor, nicotinic, alpha polypeptide 7 | Mus musculus |