Title : Interferon-γ decreases ATP-binding cassette subfamily G member 1-mediated cholesterol efflux through small ubiquitin-like modifier/ubiquitin-dependent liver X receptor-α degradation in macrophages.

Pub. Date : 2021 Dec

PMID : 33125792






1 Functional Relationships(s)
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1 The process was dependent on its interactions with phosphorylated signal transducer and activator of transcription 1 (p-STAT1) and protein inhibitor of activated STAT 1 (PIAS1), because both fludarabine and PIAS1 shRNA reversed the decrease in LXR-alpha protein expression induced by IFN-gamma. fludarabine interferon gamma Homo sapiens