Title : NR4A1 counteracts JNK activation incurred by ER stress or ROS in pancreatic β-cells for protection.

Pub. Date : 2020 Dec

PMID : 33124187






1 Functional Relationships(s)
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1 We found that NR4A1 increased the expression of cbl-b (an E3 ligase); knocking down cbl-b expression increased MKK4 and p-JNK levels under ER stress or ROS conditions. Reactive Oxygen Species Casitas B-lineage lymphoma b Mus musculus