Title : Mifepristone as a Potential Therapy to Reduce Angiogenesis and P-Glycoprotein Associated With Glioblastoma Resistance to Temozolomide.

Pub. Date : 2020

PMID : 33123485






2 Functional Relationships(s)
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1 After a 3-week treatment, the mifepristone/temozolomide regimen had decreased the level of VEGF and P-gp and significantly reduced tumor proliferation (detected by PET/CT images based on 18F-fluorothymidine uptake). Temozolomide ATP binding cassette subfamily B member 1 Homo sapiens
2 After the mifepristone/temozolomide treatment ended, however, the values of VEGF, P-gp, and MGMT increased and reached control levels by 14 weeks post-treatment. Temozolomide ATP binding cassette subfamily B member 1 Homo sapiens