Title : Acid-sensing ion channels regulate nucleus pulposus cell inflammation and pyroptosis via the NLRP3 inflammasome in intervertebral disc degeneration.

Pub. Date : 2021 Jan

PMID : 33111436






1 Functional Relationships(s)
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1 ROS activate the NF-kappaB signalling pathway, thus promoting NLRP3 inflammasome activation and IL-1beta release, both of which promote NP degeneration. Reactive Oxygen Species NLR family, pyrin domain containing 3 Rattus norvegicus