Title : Perdurable PD-1 blockage awakes anti-tumor immunity suppressed by precise chemotherapy.

Pub. Date : 2021 Jan 10

PMID : 33091531






1 Functional Relationships(s)
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1 Here, we synthesized a redox-sensitive nano-micelle formed by hyaluronic acid (HA) conjugated with d-alpha-tocopherol succinate (TOS) using a disulfide bond as the linker (HA-SS-TOS, HSST), which could actively accumulate to the tumor sites and metastasis cancer cells with high expression of CD44. Hyaluronic Acid N-deacetylase and N-sulfotransferase 1 Homo sapiens