Protein Name N-deacetylase and N-sulfotransferase 1
Organism Homo sapiens
Gene ID 3340
Gene Symbol

NDST1

UniProt P52848 (NDST1_HUMAN), E7EVJ3 (E7EVJ3_HUMAN), A8K8T3 (A8K8T3_HUMAN), B7Z1Q0 (B7Z1Q0_HUMAN)
Relationships Total Number of functionally related compound(s) : 37
Total Number of Articles : 41
Description

N-deacetylase and N-sulfotransferase 1

Gene Summary

This gene encodes a member of the heparan sulfate/heparin GlcNAc N-deacetylase/ N-sulfotransferase family. The encoded enzyme is a type II transmembrane protein that resides in the Golgi apparatus. The encoded protein catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate to nitrogen of glucosamine in heparan sulfate. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

synonyms
  • bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 1
  • HSNST 1
  • N-Deacetylase-N-sulfotransferase 1
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Properties