Title : Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex.

Pub. Date : 2020

PMID : 33088274






3 Functional Relationships(s)
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1 Our mechanistic exploration showed that repeated N2O exposure increased burst firing activity and that the expression levels of BDNF with nNOS activation were dependent in the mPFC. Nitrous Oxide brain derived neurotrophic factor Homo sapiens
2 In summary, our results indicated that N2O exposure enhances BDNF expression levels and burst firing rates in an nNOS activation dependent manner, which might underlie the pharmacological mechanism of the antidepressant-like effects of N2O exposure. Nitrous Oxide brain derived neurotrophic factor Homo sapiens
3 In summary, our results indicated that N2O exposure enhances BDNF expression levels and burst firing rates in an nNOS activation dependent manner, which might underlie the pharmacological mechanism of the antidepressant-like effects of N2O exposure. Nitrous Oxide brain derived neurotrophic factor Homo sapiens