Title : Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation.

Pub. Date : 2020 Oct 21

PMID : 33087499






1 Functional Relationships(s)
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1 AhR pathway activation by an enriched tryptophan diet, treatment with the AhR ligand producer L. reuteri, or pharmacological stimulation using 6-formylindolo (3,2-b) carbazole (Ficz) decreased immunopathology in NOD/DQ8 mice exposed to gluten. Tryptophan aryl hydrocarbon receptor Homo sapiens